Drug interactions of azole antifungals

Drug interactions can occur when two or more medications are simultaneously given, and one drug increases decreases the effectiveness of other. Azole antifungal agents show a wide range with other drugs. Failure to recognize drug–drug interaction may produce harm patient, including enhanced toxicity concomitantly administered medication. Most azole antifungals pharmacokinetic type. This article reviews clinically relevant commonly used - fluconazole itraconazole.